| DOTS-MEGA-PACK DOTS Collectible Tiles 41913-1 Mega Pack | 2021 | 22 | — | — | — |
| DOTS-SERIES-3 DOTS Collectible Tiles Series 3 | 2021 | 16 | — | — | — |
| DOTS-SERIES-4 DOTS Collectible Tiles Series 4 | 2021 | 24 | — | — | — |
| DOTS-SERIES-5 DOTS Collectible Tiles Series 5 | 2021 | 16 | — | — | — |
| HUBBLEMOSAIC Hubble Image Mosaic | 2021 | 179 | — | — | — |
| VIDIYO-TILES VIDIYO Tiles - Database Set | 2021 | 80 | — | — | — |
| WIZARD-CARDS Wizard Cards Tiles | 2021 | 16 | — | — | — |
| 88015 Battery Box | 2021 | 1 | £30 | — | — |
| 88017 Large Angular Motor · retired 21 Dec 2024 | 2021 | 1 | £30 | — | — |
| 88018 Medium Angular Motor · retired 11 Jul 2024 | 2021 | 1 | £25 | — | — |
| 40450 Amelia Earhart Tribute · retired 31 Dec 2021 | 2021 | 200 | — | £19 | — |
| 40485 FC Barcelona Celebration · retired 31 Dec 2021 | 2021 | 178 | — | £46 | — |
| 40486 Adidas Originals Superstar · retired 31 Dec 2021 | 2021 | 92 | — | £22 | — |
| 40512 Fun and Funky VIP Add On Pack | 2021 | 148 | — | £4 | — |
| 40513 Spooky VIP Add On Pack | 2021 | 119 | — | £7 | — |
| 40514 Winter Wonderland VIP Add On Pack | 2021 | 139 | — | — | — |
| 5006744 Ulysses Space Probe | 2021 | 236 | — | — | — |
| 5006745 Carousel | 2021 | 136 | — | — | — |
| 5006746 Swing Ship Ride | 2021 | 152 | — | — | — |
| 5006890 Rebuildable Flying Car | 2021 | 113 | — | — | — |
| 5006911 Vintage Camera | 2021 | 179 | — | — | — |
| 6351965 Rickshaw and Paifang Gateway | 2021 | 168 | — | £20 | — |
| 6373603 Ulysses Space Probe | 2021 | 236 | — | — | — |
| 6373621 Swing Ship Ride | 2021 | 152 | — | — | — |
| 6374338 Swing Ship Ride | 2021 | 152 | — | — | — |
| 6384693 Little Red Riding Hood Book | 2021 | 151 | — | — | — |
| 6384693-3 Little Red Riding Hood | 2021 | 0 | — | — | — |
| 6384694 Alice's Adventures in Wonderland Book | 2021 | 144 | — | — | — |
| 6384694-4 Alice in Wonderland | 2021 | 0 | — | — | — |
| 6384695 Jack and the Beanstalk Book | 2021 | 149 | — | — | — |
| 6384695-2 Jack and the Beanstalk | 2021 | 0 | — | — | — |
| 6384696 Hansel and Gretel Book | 2021 | 154 | — | £21 | — |
| 6384705 TMALL 1st Anniversary Exclusive Set | 2021 | 9 | — | — | — |
| 6385891 Brick Lab | 2021 | 145 | — | — | — |
| 6386184 LEGO Masters participants gift | 2021 | 107 | — | — | — |
| 6387807 Rebuildable Flying Car | 2021 | 113 | — | — | — |
| 6387808 Rebuildable Flying Car | 2021 | 113 | — | — | — |
| 6392343 Vintage Camera | 2021 | 179 | — | — | — |
| 6392344 Vintage Camera | 2021 | 179 | — | — | — |
| 94107 Developer | 2021 | 82 | — | — | — |
| FOOTSHOP Footshop Meets Adidas & LEGO Special Custom Re-build Kit | 2021 | 245 | — | — | — |
| UNITY Unity x Lego Minifigure | 2021 | 8 | — | — | — |
| WINDTURBINE Wind Turbine | 2021 | 36 | — | — | — |
| 6373618 Japan Carousel | 2021 | 136 | — | — | — |
| 10293 Santa's Visit · retired 31 Dec 2023 | 2021 | 1,445 | £90 | £107+19% | — |
| 30579 Easter Chick Egg · retired 31 Dec 2021 | 2021 | 52 | £3 | £4+2% | — |
| 30580 Santa Claus · retired 31 Dec 2022 | 2021 | 69 | — | £4 | — |
| 40417 Year of the Ox | 2021 | 168 | — | £7 | — |
| 40449 Easter Bunny's Carrot House · retired 31 Dec 2021 | 2021 | 232 | — | £10 | — |
| 40462 Valentine's Brown Bear · retired 31 Dec 2022 | 2021 | 245 | £13 | £10-26% | — |
| 40463 Easter Bunny · retired 31 Dec 2022 | 2021 | 293 | £13 | £13-6% | — |
| 40484 Santa's Front Yard · retired 31 Dec 2021 | 2021 | 317 | — | £19 | — |
| 40489 Mr. and Mrs. Claus' Living Room | 2021 | 344 | — | — | — |
| 40493 Spider & Haunted House Pack · retired 31 Dec 2021 | 2021 | 132 | — | £18 | — |
| 40494 Polar Bear & Gift Pack · retired 31 Dec 2021 | 2021 | 142 | £9 | £12+33% | — |
| 40497 Halloween Owl · retired 31 Dec 2022 | 2021 | 228 | £13 | £12-12% | — |
| 40498 Christmas Penguin · retired 31 Dec 2022 | 2021 | 244 | £13 | £18+34% | — |
| 40499 Santa's Sleigh · retired 31 Dec 2025 | 2021 | 343 | £40 | £29-27% | — |
| 41690 Friends Advent Calendar 2021 · retired 31 Dec 2021 | 2021 | 370 | £20 | — | — |
| 60303 City Advent Calendar 2021 · retired 31 Dec 2021 | 2021 | 349 | £20 | £20-2% | — |
| 6345925 Micro Ox | 2021 | 24 | — | — | — |
| 6392262 Christmas 4-in-1 Builds | 2021 | 60 | — | — | — |
| 75307 Star Wars Advent Calendar 2021 · retired 31 Dec 2021 | 2021 | 335 | £25 | £29+16% | — |
| 76196 Marvel The Avengers Advent Calendar 2021 · retired 31 Dec 2021 | 2021 | 298 | £25 | £36+44% | — |
| 76390 Harry Potter Advent Calendar 2021 · retired 31 Dec 2021 | 2021 | 274 | £25 | £22-12% | — |
| BLUEGHOST Blue Ghost | 2021 | 43 | — | — | — |
| 2000414-3 Starter Kit | 2021 | 234 | — | — | — |
| 30343 McLaren Elva · retired 31 Dec 2022 | 2021 | 85 | — | £4 | — |
| 76900 Koenigsegg Jesko · retired 31 Dec 2023 | 2021 | 280 | £20 | £23+15% | — |
| 76901 Toyota GR Supra · retired 31 Dec 2023 | 2021 | 299 | £20 | £22+12% | — |
| 76902 McLaren Elva · retired 31 Dec 2022 | 2021 | 263 | £18 | £18+2% | — |
| 76903 Chevrolet Corvette C8.R Race Car and 1969 Chevrolet Corvette · retired 31 Dec 2022 | 2021 | 512 | £35 | £41+16% | — |
| 76904 Mopar Dodge//SRT Top Fuel Dragster and 1970 Dodge Challenger T/A · retired 31 Dec 2022 | 2021 | 627 | £55 | £45-19% | — |
| 76905 Ford GT Heritage Edition and Bronco R · retired 31 Dec 2022 | 2021 | 660 | £45 | £87+92% | — |
| 30388 Imperial Shuttle · retired 31 Dec 2021 | 2021 | 85 | — | £6 | — |
| 40451 Tatooine Homestead · retired 31 Dec 2021 | 2021 | 217 | — | £31 | — |
| 40483 Luke Skywalker's Lightsaber · retired 31 Dec 2021 | 2021 | 173 | — | £124 | — |
| 66674 Skywalker Adventures Pack · retired 31 Dec 2021 | 2021 | 644 | — | — | — |
| 75295 Millennium Falcon Microfighter · retired 31 Dec 2022 | 2021 | 101 | £9 | £8-10% | — |
| 75296 Darth Vader Meditation Chamber · retired 31 Dec 2022 | 2021 | 663 | £60 | £55-8% | — |
