| 2000556 Six Bricks | 2021 | 12 | — | — | — |
| 2000722 SPIKE Essential Replacement Pack 1 | 2021 | 97 | — | — | — |
| 2000723 SPIKE Essential Replacement Pack 2 | 2021 | 16 | — | — | — |
| 45345 SPIKE Essential · retired 20 Jan 2026 | 2021 | 442 | £365 | — | — |
| 45400 BricQ Motion Prime · retired 31 Aug 2025 | 2021 | 562 | £155 | — | — |
| 45401 BricQ Motion Essential · retired 31 Aug 2025 | 2021 | 523 | £155 | — | — |
| 45607 Small Angular Motor | 2021 | 1 | — | — | — |
| 45608 3×3 Color Light Matrix | 2021 | 1 | — | — | — |
| 45609 Small Hub · retired 20 Jan 2026 | 2021 | 2 | £245 | — | — |
| 45612 Small Hub Battery · retired 20 Jan 2026 | 2021 | 1 | £80 | — | — |
| 45681 SPIKE Prime Expansion Set (v2) · retired 20 Jan 2026 | 2021 | 604 | £145 | £140-4% | — |
| 2000472 FLL Trophy Small - Build it Yourself | 2021 | 233 | — | — | — |
| 2000473 FLL Trophy Medium- Build it Yourself | 2021 | 280 | — | — | — |
| 2000474 FLL Trophy Large- Build it Yourself | 2021 | 438 | — | — | — |
| 2000475 FLL Competitions Medal - Build it Yours | 2021 | 18 | — | — | — |
| 45816 CARGO CONNECT Challenge Kit · retired 31 Dec 2023 | 2021 | 1,920 | — | — | — |
| 45817 CARGO CONNECT Explore Set · retired 31 Dec 2023 | 2021 | 885 | — | — | — |
| 45818 CARGO CONNECT Discover Set | 2021 | 77 | — | — | — |
| 30413 Flower Cart · retired 31 Dec 2021 | 2021 | 55 | — | — | — |
| 30414 Emma's Magical Box · retired 31 Dec 2022 | 2021 | 67 | — | — | — |
| 41439 Cat Grooming Car · retired 31 Dec 2022 | 2021 | 60 | £9 | — | — |
| 41440 Heartlake City Bakery · retired 31 Dec 2021 | 2021 | 99 | £15 | — | — |
| 41441 Horse Training and Trailer · retired 31 Dec 2022 | 2021 | 148 | £25 | — | — |
| 41442 Vet Clinic Rescue Buggy · retired 31 Dec 2021 | 2021 | 100 | £9 | — | — |
| 41443 Olivia's Electric Car · retired 31 Dec 2023 | 2021 | 183 | £13 | — | — |
| 41444 Heartlake City Organic Café · retired 31 Dec 2022 | 2021 | 314 | £25 | — | — |
| 41445 Vet Clinic Ambulance · retired 31 Dec 2021 | 2021 | 304 | £28 | — | — |
| 41446 Heartlake City Vet Clinic · retired 31 Dec 2021 | 2021 | 258 | £35 | — | — |
| 41447 Heartlake City Park · retired 31 Dec 2021 | 2021 | 432 | £35 | — | — |
| 41448 Heartlake City Movie Theater · retired 31 Dec 2022 | 2021 | 451 | £45 | — | — |
| 41449 Andrea's Family House · retired 31 Dec 2022 | 2021 | 802 | £60 | — | — |
| 41450 Heartlake City Shopping Mall · retired 31 Dec 2022 | 2021 | 1,032 | £90 | £119+32% | — |
| 41662 Olivia's Flamingo Cube · retired 31 Dec 2021 | 2021 | 41 | £9 | — | — |
| 41663 Emma's Dalmatian Cube · retired 31 Dec 2021 | 2021 | 41 | £9 | — | — |
| 41664 Mia's Pug Cube · retired 31 Dec 2021 | 2021 | 40 | £9 | — | — |
| 41665 Stephanie's Cat Cube · retired 31 Dec 2021 | 2021 | 46 | £9 | — | — |
| 41666 Andrea's Bunny Cube · retired 31 Dec 2021 | 2021 | 45 | £9 | — | — |
| 41667 Olivia's Gaming Cube · retired 31 Dec 2021 | 2021 | 64 | £9 | — | — |
| 41668 Emma's Fashion Cube · retired 31 Dec 2021 | 2021 | 58 | £9 | — | — |
| 41669 Mia's Soccer Cube · retired 31 Dec 2021 | 2021 | 56 | £9 | — | — |
| 41670 Stephanie's Ballet Cube · retired 31 Dec 2021 | 2021 | 60 | £9 | — | — |
| 41671 Andrea's Swimming Cube · retired 31 Dec 2021 | 2021 | 59 | £9 | — | — |
| 41677 Forest Waterfall · retired 31 Dec 2023 | 2021 | 93 | £9 | £6-33% | — |
| 41679 Forest House · retired 31 Dec 2022 | 2021 | 326 | £25 | — | — |
| 41681 Forest Camper Van and Sailboat · retired 31 Dec 2022 | 2021 | 487 | £45 | £29-36% | — |
| 41682 Heartlake City School · retired 31 Dec 2022 | 2021 | 605 | £60 | — | — |
| 41683 Forest Horseback Riding Center · retired 31 Dec 2022 | 2021 | 511 | £60 | — | — |
| 41684 Heartlake City Grand Hotel · retired 31 Dec 2022 | 2021 | 1,308 | £90 | — | — |
| 41685 Magical Funfair Roller Coaster · retired 31 Dec 2022 | 2021 | 974 | £90 | — | — |
| 41686 Magical Acrobatics · retired 31 Dec 2022 | 2021 | 223 | £18 | — | — |
| 41687 Magical Funfair Stalls · retired 31 Dec 2022 | 2021 | 361 | £25 | — | — |
| 41688 Magical Caravan · retired 31 Dec 2022 | 2021 | 348 | £45 | — | — |
| 41689 Magical Ferris Wheel and Slide · retired 31 Dec 2022 | 2021 | 545 | £55 | — | — |
| 41691 Doggy Day Care · retired 31 Dec 2022 | 2021 | 221 | £18 | — | — |
| 41692 Vet Clinic Rescue Helicopter · retired 31 Dec 2021 | 2021 | 249 | £18 | — | — |
| 41693 Surfer Beachfront · retired 31 Dec 2022 | 2021 | 685 | £60 | — | — |
| 472102 Emma & Baby Panda | 2021 | 8 | — | — | — |
| 562101 Performing Dog | 2021 | 19 | — | — | — |
| 562102 Dressing Table | 2021 | 32 | — | — | — |
| 562103 Cat Grooming Salon | 2021 | 25 | — | — | — |
| 562104 Ice Cream Shop | 2021 | 44 | — | — | — |
| 562105 Squirrel's Tree House | 2021 | 29 | — | — | — |
| 562106 Stephanie's Cookie-Kitchen | 2021 | 35 | — | — | — |
| 66673 Animal Gift Set · retired 31 Dec 2021 | 2021 | 431 | — | — | — |
| 5006294 Mechanical Pencil with Minifigure · retired 29 Jun 2026 | 2021 | 5 | £7 | — | — |
| 5006608 3-Drawer Storage (Gray) · retired 2 Jan 2026 | 2021 | 4 | £57 | — | — |
| 5006655 Porsche Welcome Pack | 2021 | 1 | — | — | — |
| 5006771 VIDIYO Sticker Sheet | 2021 | 2 | — | — | — |
| 5006772 VIDIYO VIP Welcome Pack | 2021 | 2 | — | — | — |
| 5007289 Brick Scooper Set · retired 1 Mar 2024 | 2021 | 1 | £14 | — | — |
| 52214 Star Wars Pencils with Topper | 2021 | 1 | — | — | — |
| 854084 Pearl White Brick Key Chain · retired 23 Feb 2023 | 2021 | 1 | £5 | — | — |
| DUTCHVANDER "Dutch" Vander | 2021 | 4 | — | — | — |
| FY7690 adidas Ultraboost DNA x LEGO - Men's Shoes | 2021 | 4 | — | — | — |
| 30392 Hermione's Study Desk · retired 31 Dec 2022 | 2021 | 31 | — | £2 | — |
| 40452 Hogwarts Gryffindor Dorms · retired 31 Dec 2021 | 2021 | 148 | — | £49 | — |
| 40500 Wizarding World Minifigure Accessory Set · retired 31 Dec 2021 | 2021 | 33 | £13 | £15+10% | — |
| 76382 Hogwarts Moment: Transfiguration Class · retired 31 Dec 2022 | 2021 | 241 | £25 | £21-16% | — |
| 76383 Hogwarts Moment: Potions Class · retired 31 Dec 2022 | 2021 | 271 | £25 | £25+0% | — |
| 76384 Hogwarts Moment: Herbology Class · retired 31 Dec 2021 | 2021 | 233 | £28 | £45+61% | — |
